Study of the Interaction of Albendazole with Benzoic Acid. I
نویسندگان
چکیده
CRISTINA TRANDAFIRESCU1, FLORIN BORCAN2*, CRISTINA DEHELEAN3, ZOLTAN SZABADAI4, MIRELA NICOLOV4, CODRUTA SOICA1 1University of Medicine and Pharmacy Victor Babes, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 2 EftimieMurgu Sq., 300041, Timisoara, Romania 2University of Medicine and Pharmacy Victor Babes, Faculty of Pharmacy, Department of Analytical Chemistry, 2 EftimieMurgu Sq., 300041, Timisoara, Romania 3University of Medicine and Pharmacy Victor Babes, Faculty of Pharmacy, Department of Toxicology, 2 EftimieMurgu Sq., 300041, Timisoara, Romania 4University of Medicine and Pharmacy Victor Babes, Faculty of Pharmacy, Department of Pharmaceutical Physics, 2 Eftimie Murgu Sq., 300041, Timisoara, Romania
منابع مشابه
Acoustical Studies of Some Derivatives of 4-Amino Benzoic Acid in 1, 4-Dioxane and Dimethyl Formamide at 308.15 K
The ultrasonic velocity, density and viscosity of some Schiff bases of 4-amino benzoic acid were measured in 1,4-dioxane and dimethylformamide at 308.15 K. Various acoustical properties such as isentropic compressibility (ks), Rao’s molar sound function (Rm), the Van der Waals constant (b), molar compressibility (W), inter molecular free len...
متن کاملKinetic Studies of the Catalytic Oxidation of Toluene to Benzoic Acid in the Liquid Phase
The catalytic oxidation of toluene to benzoic acid in the liquid phase has been studied in an un-stirred tank reactor. Low concentration of acetic acid was added in order to increase the solubility of the catalyst in toluene. The dependence of the rate of reaction on the concentration of toluene catalyst and oxygen pressure was studied. It has been suggested that liquid phase oxidation of t...
متن کاملDetermination of the effects of food preservatives benzoic acid and sodium nitrate on lifespan, fertility and physical growth in Caenorhabditis elegans
Presently, the use of protective food additives such as benzoic acid and sodium nitrate is quite common. However, it was found that these additives, which initially appeared to be harmless, led to the emergence of a number of health problems. Cancer and diseases and deaths with no apparent causes are among the leading concerns. Therefore, the studies which can reveal the genotoxic potential of ...
متن کاملCharacterization of inhibitory effects of the potential therapeutic inhibitors, benzoic acid and pyridine derivatives, on the monophenolase and diphenolase activities of tyrosinase
Objective(s):Involvement of tyrosinase in the synthesis of melanin and cell signaling pathway has made it an attractive target in the search for therapeutic inhibitors for treatment of different skin hyperpigmentation disorders and melanoma cancers. Materials and Methods: In the present study, we conducted a comprehensive kinetic analysis to understand the mechanisms of inhibition imposed by 2-...
متن کاملApplication of Hammett Constant for Prediction of Acidity Properties of Substituted Benzoic Acid
Hammett constants (σ) can be important factor to understanding substitution and position effects on benzoic acid. This report describes a computational study of ∆G◦ and σ for six substituted benzoic acid (X= F,Cl ,OH ,NH2 ,CN,NO2 )and phenylacetic acid substituted (X=OH ,NH2 ) at para and meta positions ingas and aqueousphases by DFT method and comparesit to available experimental and theoretic...
متن کامل